Tinospora cordifolia guduchi, a reservoir plant for. Comparative antimicrobial activity of ethanolic and. The purpose of this study was to evaluate the antimicrobial effect of rubia cordifolia root water and methanol extracts on various microorganisms using the agar well diffusion method and to. Tinospora cordifolia, antioxidant activity, medicinal plant, antihyperglycemic activity. Tinospora cordifolia chemical constituents and medicinal. Antimicrobial efficiency of tinospora cordifolia and hymenocallis littoralis, medicinal plants were examined using ethanol, methanol, chloroform, dichloromethane, ethyl acetate as solvents a nd found that all the plants parts showed significant activity against all pathogens. The antimicrobial activities of tinospora cordifolia leaf extracts are compared with standard antibiotics such as amoxicillin, which was used as positive controls.
The chemical constituents and diverse pharmacological. Antimicrobial susceptibility assay of tinospora cordifolia leaf extract table 2 antimicrobial susceptibility assay of tinospora cordifolia stem extract sr. The results confirmed that tinospora cordifolia is a rich reservoir of endophytic bacteria which are good source of biologically active compounds responsible for antimicrobial activity. Azadiracta indica, acacia nilotica, tinospora cordifolia.
The present study was aimed at determining the activity of aqueous and methanolic extracts of tinospora cordifolia aetc and metc against salmonella typhimurium. The silver ions, as well as silver nanoparticles, were known to have strong antimicrobial activities 2427. Based on ethno pharmacological and taxonomic information, antimicrobial activities of crude aqueous extracts of five medicinal plants including leaves of moringa oleifera, azadirachta indica. Issn 23203862 evaluation of anticancer activity of stem. Immunestimulatory and therapeutic activity of tinospora. Research article screening of antimicrobial activity of. The zones of inhibition in diameter cm recorded for ethanol, chloroform and aqueous are depicted in table 1. It works because pathogens cannot mutate to avoid the antimicrobial. Tinospora cordifolia guduchi or amrita is an important drug of ayurvedic system of medicine and found mention in various classical texts for the treatment of diseases such as jaundice, fever, diabetes. Present communication reports the scientific evaluation of tinospora cordifolia for its medicinal efficacy which includes phytochemical screening, antimicrobial, antioxidant, and anticancer activities. Acorus calamus sweet flag is a wellknown traditional herb used in india. Evaluation of antimicrobial activity and phytochemical. The results of a preliminary antimicrobial screening of the methanol extracts of zingiber officinale, asteracantha longifolia, citrus acida, salacia microsperma and tinospora cordifolia are reported.
Anticancer activity tinospora cordifolia shows anticancer activity, this activity is mostly shown in animal models. The present study aimed to assess the antimicrobial activity of different concentrations of commercially available t. In vitro antibacterial effect of tinospora cordifolia. Tinospora cordifolia, which is known by the common names heartleaved moonseed, gaduchi, and giloya, is an herbaceous vine of the family menispermaceae indigenous to the tropical areas of. Antifungal and phytochemical properties of tinospora. The antimicrobial activity was determined by measuring the diameter of zone of inhibition. Pdf antimicrobial activity of crude aqueous extracts of. The antimicrobial activity of silver nanoparticles synthesized from leaves and stem of tinospora cordifolia. Scientific validation of the medicinal efficacy of.
Tinospora cordifolia m enispermaceae, matured stems was collected locally at thanjavur. Anticancer, cytotoxicity, invitro, mdamb231, breast cancer, tinospora cordifolia 1. Lysozymes act as a potent antimicrobial compound against grampositive species shimada et al. The common names are amrita and guduchi and belong to the. The antimicrobial property of tinospora cordifolia has been tested against a variety of microorganisms in the literature. Evaluation of antimicrobial activity and phytochemical screening of extracts oftinospora cordifolia against some pathogenic microbes dinesh bansal 1, pragya bhasin, anita punia1, and anita r. A study of antimicrobial activity of few medicinal herbs. It has been traditionally used for treatment of diabetes, jaundice, chronic diarrhoea, cancer, dermatological diseases, general debility, and asthma. Tinospora cordifolia leaf extracts and investigation of their antibacterial effects for the first time. The isolated bacterial were first cultured in a nutrient broth. Tinospora cordifolia possess very good antibacterial activity which makes them a potent source of antibacterial agent.
Antibacterial activity of aqueous, ethanol and chloroform extracts of leaves and stem of tinospora cordifolia hook. Antibacterial properties of biologically synthesized chitosan nanoparticles along with leaves extract. Review of biological activities of tinospora cordifolia. The hydroalcoholic extract of tinospora cordifolia have been reported to be rich in flavonoids, alkaloids and glycosides 11 and has been shown to exhibit antibacterial property against certain. Introduction i t is the need of hour to show the effectiveness of the drug in a disease by laboratory findings. An in vitro study was undertaken in which extract of t.
Tinospora cordifolia belonging to the family menispermaceae. Therefore antimicrobial silver is now used extensively to combat organisms in wounds and burns. Tinospora cordifolia was shown to possess cytotoxic activity against human breast cancer cells. Review of biological activities of tinospora cordifolia abstract. The treatment of infectious diseases with antimicrobial agents continues to present problems in modernday. Antimicrobial activity, guduchi, guduchi ghana, physicochemical, tinospora cordifolia. A study of antimicrobial activity of few medicinal herbs parastoo karimi alavijeh, parisa karimi alavijeh and devindra sharma. This study was intended to investigate the antioxidant properties and antimicrobial activity of methanolic extract of tinospora. Mahesh et al 20085 carried out antimicrobial activity of some important medicinal plant against plant and human pathogens on the methanol leaf extracts of acacia nilotica, sida cordifolia, tinospora cordifolia,withania somnifera and ziziphus mauritiana showed significant antibacterial activity. Antimicrobial activity of some medicinal plants from india. Viola species and tinospora cordifolia as herbal antibiotics. Antibacterial activity of tinospora cordifolia request pdf.
Studies on in vitro antibacterial activity of tinospora. The extraction of alkaloid palmatine from tinospora cordifolia by using response. Tinospora cordifolia is an important herb of tropical india in ayurvedic system of medicines. In vitro antimicrobial activity of tinospora cordifolia. The present study deals with the antimicrobial activity and phytochemical screening of the two medicinal plants, tinospora cordifolia and euphorbia hirta those are commonly available in india. Antifungal activity of various extract of leaves of tinospora cordifolia, azadirachta indica and ocimum sanctum would lead to the establishment of some compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin. Four different solvents ethyl acetate, chloroform, diethyl ether and aqueous were used to obtain extracts of bacterial endophytes for qualitative phytochemical analysis. Methanolic extract of tinospora cordifolia showed significant anticancer activity against mdamb231 human breast cancer cell line. Phytochemical, antioxidant, antimicrobial, and protein.
It is revealed that the ethanolic extracts exhibited significant antibacterial activity against proteus vulgaris, escherichia coli and moderate activity. Tinospora cordifolia is a popular medicinal plant which is used in several traditional medicines to cure various diseases. The study was performed to check the chemical, antioxidant, antimicrobial and protein binding qualities of the hydroethanolic extract of tinospora cordifolia tc. Thoms were tested on clinical isolates of urinary pathogens viz. Phenylpropanoid glycosides and tetrahydrofuranlignan glycosides from the adaptogenic plant drugs tinospora cordifolia and drypetes roxburghii. Methods to determine antimicrobial activity 1yazan ismail, 2mohammed wedyan, 1muad alzuabe and 2salim abderrahman 1department of allied medical. Miers plant extracts against selected clinical isolates mamta devi, anchal sharma, navdeep, sudhir saroea.
The antibacterial activity of the hydroalcoholic extracts of tinospora cordifolia was determined by agarwell diffusion method. Results of antimicrobial activity revealed that these. View tinospora cordifolia research papers on academia. Antibacterial properties of biologically synthesized. Original article in vitro study of antimicrobial activity. Ic50 values of tc methanolic extract with respect to mdamb231 were. Antimicrobial activity of crude aqueous extracts of moringa oleifera, azadirachta indica, carica papaya, tinospora cordifolia and curcuma longa against certain bacterial pathogens june 2018. Antioxidant and antibacterial activity of acorus calamus.
There were only limited studies done on both hydrophilic and hydrophobic extracts of a. Tinospora cordifolia an overview sciencedirect topics. Antioxidant and antimicrobial properties of tinospora. Comparative antimicrobial activity of ethanolic and aqueous extract of tinospora cordifolia krishnadutt pratihast, rajneesh kumar and sudhanshu kumar bharti abstract the present study was designed. This study was intended to investigate the antioxidant properties and antimicrobial activity of methanolic extract of tinospora crispa stems extracted using soxhlet extraction method. Tinospora cordifolia is one of the constituents of several ayurvedic preparations used in general debility, dyspepsia, fever and urinary. Introduction among plants of economic importance, medicinal and aromatic plants have played a. The methanolic extract would be studied further for isolation and characterization of active components for lead optimization studies. The antibacterial activity of tinospora cordifoliaextracts has been assayed against various gram positive and gram negative organisms. Preliminary phytochemical screening and evaluation of free radical scavenging activity of tinospora cordifolia. The antimicrobial activity of tc stem extracts was. Materials and methods plant collection and authentification. The aim of the present study was to evaluate the antimicrobial activity of tinospora cordifolia extracts against three standard atcc strains of escherichia coli, staphylococcus aureus and.
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